载入中...
 
     
 
载入中...
时 间 记 忆
载入中...
最 新 评 论
载入中...
专 题 分 类
载入中...
最 新 日 志
载入中...
最 新 留 言
载入中...
搜 索
用 户 登 录
载入中...
友 情 连 接
博 客 信 息
载入中...


 
 
载入中...
   
 
 
狄文教授--晚期卵巢癌新辅助化疗研究进展
[ 2008-11-3 8:56:00 | By: diwen ]
 

摘 要:目前卵巢癌的标准治疗方案是以手术为主,辅以术后化疗,实现满意肿瘤细胞减灭术是手术的目的 .但患者出现明显症状时,疾病大多已处于晚期,多数患者无法实行满意肿瘤细胞减灭术.新辅助化疗结合间隔手术作为晚期卵巢癌患者的替代治疗方案具有较好的应用前景.文章就晚期卵巢癌新辅助化疗的研究进展作一综述.
关键词:卵巢癌;新辅助化疗;间隔手术;满意肿瘤细胞减灭术;预后
分类号:R737.31 文献标识码:A

文章编号:0258-5898(2008)05-0592-04

Research progress in neoadjuvant chemotherapy for advanced ovarian cancer

HU Ke  DI Wen 

作者简介:胡柯(1981-),男,四川泸州人,博士;电子信箱:huke1981@gmail.com.
作者单位:胡柯(上海交通大学,医学院仁济医院妇产科,上海,200127) 
     狄文(上海交通大学,医学院仁济医院妇产科,上海,200127) 

参考文献:

[1]Jemal A,Siegel R,Ward E,et al.Cancer statistics,2006[J].CA Cancer J Clin,2006,56(2):106-130.
[2]Bristow RE,Tomacruz RS,Armstrong DK,et al.Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era:a meta-analysis[J].J Clin Oncol,2002,20(5):1248-1259.
[3]Lee SJ,Kim BG,Lee JW,et al.Preliminary results of neoadjuvant chemotherapy with paclitaxel and cisplatin in patients with advanced epithelial ovarian cancer who are inadequate for optimum primary surgery[J].J Obstet Gynaecol Res,2006,32(1):99-106.
[4]Pectasides D,Farmakis D,Koumarianou A.The role of neoadjuvant chemotherapy in the treatment of advanced ovarian cancer[J].Oncology,2005,68(1):64-70.
[5]Steed H,Oza AM,Murphy J,et al.A retrospective analysis of neoadjuvant platinum-based chemotherapy versus up-front surgery in advanced ovarian cancer[J].Int J Gynecol Cancer,2006,16 (Suppl 1):47-53.
[6]Le T,Alshaikh G,Hopkins L,et al.Prognostic significance of postoperative morbidities in patients with advanced epithelial ovarian cancer treated with neoadjuvant chemotherapy and delayed primary surgical debulking[J].Ann Surg Oncol,2006,13(12):1711-1716.
[7]Le T,Faught W,Hopkins L,et al.Primary chemotherapy and adjuvant tumor debulking in the management of advanced-stage epithelial ovarian cancer[J].Int J Gynecol Cancer,2005,15(5):770-775.
[8]Bristow RE,Chi DS.Platinum-based neoadjuvant chemotherapy and interval surgical cytoreduction for advanced ovarian cancer:a meta-analysis[J].Gynecol Oncol,2006,103(3):1070-1076.
[9]Inciura A,Simavicius A,Juozaityte E,et al.Comparison of adjuvant and neoadjuvant chemotherapy in the management of advanced ovarian cancer:a retrospective study of 574 patients[J].BMC Cancer,2006,8(6):153.
[10]Loizzi V,Cormio G,Resta L,et al.Neoadjuvant chemotherapy in advanced ovarian cancer:a case-control study[J].Int J Gynecol Cancer,2005,15(2):217-223.
[11]Everett EN,French AE,Stone RL,et al.Initial chemotherapy followed by surgical cytoreduction for the treatment of stage Ⅲ/Ⅳ epithelial ovarian cancer[J].Am J Obstet Gynecol,2006,195(2):568-574.
[12]Hou JY,Kelly MG,Yu H,et al.Neoadjuvant chemotherapy lessens surgical morbidity in advanced ovarian cancer and leads to improved survival in stage IV disease[J].Gynecol Oncol,2007,105(1):211-217.
[13]Shibata K,Kikkawa F,Mika M,et al.Neoadjuvant chemotherapy for FIGO stage III or IV ovarian cancer:Survival benefit and prognostic factors[J].Int J Gynecol Cancer,2003,13(5):587-592.
[14]Le T,Shahriari P,Hopkins L,et al.Prognostic significance of tumor necrosis in ovarian cancer patients treated with neoadjuvant chemotherapy and interval surgical debulking[J].Int J Gynecol Cancer,2006,16(3):986-990.
[15]Berman ML.Future directions in the surgical management of ovarian cancer[J].Gynecol Oncol,2003,90(2 Pt 2):S33-39.
[16]Qayyum A,Coakley FV,Westphalen AC,et al.Role of CT and MR imaging in predicting optimal cytoreduction of newly diagnosed primary epithelial ovarian cancer[J].Gynecol Oncol,2005,96(2):301-306.
[17]Dowdy SC,Mullany SA,Brandt KR,et al.The utility of computed tomography scans in predicting suboptimal cytoreductive surgery in women with advanced ovarian carcinoma[J].Cancer,2004,101(2):346-352.
[18]Fagotti A,Fanfani F,Ludovisi M,et al.Role of laparoscopy to assess the chance of optimal cytoreductive surgery in advanced ovarian cancer:a pilot study[J].Gynecol Oncol,2005,96(3):729-735.
[19]Vergote I,Marquette S,Amant F,et al.Port-site metastases after open laparoscopy:a study in 173 patients with advanced ovarian carcinoma[J].Int J Gynecol Cancer,2005,15(5):776-779.
[20]Brockbank EC,Ind TE,Barton DP,et al.Preoperative predictors of suboptimal primary surgical cytoreduction in women with clinical evidence of advanced primary epithelial ovarian cancer[J].Int J Gynecol Cancer,2004,14(1):42-50.

 
 
发表评论:
载入中...